New PharmVar GeneFocus published for CYP2A6
PharmVar expert panel for CYP2A6 has published a review that presents allele nomenclature and includes a discussion on additional genes in the locus: CYP2A13 and CYP2A7 [PMID:39051767].
CYP2A6 metabolizes a variety of drugs including nicotine, efavirenz, tegafur, letrozole, and metronidazole for which PharmGKB has interactive pharmacokinetics pathways available. (There