TPMT allele nomenclature update published

Nomenclature for alleles of the Thiopurine Methyltransferase (TPMT) gene has been updated by the TPMT Nomenclature Committee and has been published online in Pharmacogenetics & Genomics. The committee have addressed issues such as previously existing duplication in star allele names, and has provided dbSNP rsIDs when available.

View the updated TPMT allele nomenclature on the PharmGKB haplotype page.

Read the CPIC thiopurine therapeutic dosing guidelines based on TPMT genotype.

Find out about the TPMT nomenclature committee.

Read the article:
Nomenclature for alleles of the thiopurine methyltransferase gene.

Appell ML, Berg J, Duley J, Evans W, Kennedy MA, Lennard L, Marinaki T, McLeod HL, Relling MV, Schaeffeler E, Schwab M, Weinshilboum R, Yeoh AE, McDonagh EM, Hebert JM, Klein TE, Coulthard SA. Pharmacogenet Genomics. 2013 Feb 12. (Epub ahead of print).

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