In Press: Survey Findings on Integrating Pharmacogenomics into Genomic Medicine

We’re excited to announce that our latest paper, titled “Towards an Integrated Resource for Pharmacogenomics (PGx): Survey Findings from the Genomic Medicine Communities,” is now in press in Genetics in Medicine!

This work, conducted by the ClinGen Pharmacogenomics Interpretation Committee (PGxIC, formerly the PGx Working Group), presents findings from two community surveys that gathered perspectives from over 500 participants across the PGx and genomic medicine communities. The goal of the surveys was to better understand pharmacogenomics implementation barriers, and requirements for improved integration with genomic medicine.

The results demonstrated broad consensus for the importance of standardizing terminology and developing frameworks to evaluate gene-drug clinical validity, actionability, and variant classification, modeled after ClinGen’s well-established gene-disease frameworks. Respondents also expressed support for a centralized, authoritative PGx resource to improve consistency and accessibility of PGx knowledge for clinical implementation.

We are incredibly grateful to all the survey participants for sharing their insights, and to all PGxIC members for their contributions in survey design, analysis, and manuscript preparation.

Read the article here: https://www.sciencedirect.com/science/article/abs/pii/S1098360025001765