PharmVar Launches Website
The Cytochrome P450 (CYP) Allele Nomenclature Database has transitioned to the Pharmacogene Variation Consortium at www.PharmVar.org. Please check out the PharmVar website!
Topic
PGx news
A collection of 42 issues
Announcing PharmVar
PharmVar will be taking over the allele designations for the cytochrome P450 genes from the Human Cytochrome P450 (CYP) Allele Nomenclature Database, and later expanding to become a central repository for other pharmacogenes as well. PharmGKB will partner with PharmVar to make sure PharmGKB has the most up-to-date pharmacogene allele
Pharmacogenetics/Genomics (PGx) and Depression Featured on NBC News
On August 7th, NBC News aired a segment on how pharmacogenomics can help treat patients with depression. It highlighted the story of Sarah Ellis from Sioux Falls, SD who had trouble finding a combination of antidepressant and anti-anxiety medications that did not induce debilitating adverse effects. She had tried 23
Pharmacogenomics on Nightly News with Lester Holt
The Wednesday, June 28th edition of the Nightly News with Lester Holt featured a short segment on pharmacogenomics.
The piece briefly covered the Mayo Clinic's work in expanding the use of pharmacogenomics in the clinic. Dr. Richard Weinshilboum, co-director of the pharmacogenomics program at the Mayo Clinic, was
AMIA 10x10 Virtual Pharmacogenomics course with Stanford University begins June 26, 2017
The American Medical Informatics Association (AMIA) has partnered with the Biomedical Informatics program at Stanford University to present an online course in pharmacogenomics (PGx) as part of the AMIA 10 x 10 series. The course, Pharmacogenomics, will introduce the field and cover topics relevant to PGx including pharmacology, genomics, genome
NHGRI’s Genomic Medicine X: Pharmacogenomics Meeting
On May 2 and 3, 2017, the National Human Genome Research Institute (NHGRI) held its 10th Genomic Medicine meeting, focusing on pharmacogenomics.
PharmGKB, PharmCAT and CPIC were presented, as well as a review of the deposition of PharmGKB and CPIC data to ClinVar. We thank Mary Relling from St Jude
NIGMS Director’s Early Career Investigator Lecture on antiretrovirals, PGx
On Wednesday, April 5th at 2:00 PM EST the National Institute of General Medical Sciences (NIGMS) will broadcast the NIGMS Director’s Early Career Investigator Lecture featuring a talk by Dr. Namandjé N. Bumpus entitled “Drug Metabolism, Pharmacogenetics and the Quest to Personalize HIV Treatment and Prevention”. In it,
Response to the American Academy of Pediatrics statement on codeine: let's consider CYP2D6
The American Academy of Pediatrics (AAP) issued a statement last Tuesday that codeine should not be used in children. As discussed in the article, pharmacogenetic variation can affect response to codeine, which is metabolized into its active form by the hepatic enzyme CYP2D6. Thus poor metabolizers are unlikely to benefit
Clinical implementation of PGx discussed in JAMA article
A recent article in the Journal of the American Medical Association (JAMA) discusses the current state of pharmacogenetic (PGx) implementation in the clinic. The article notes that clinical uptake of pharmacogenetics has been slow, despite data from the American Medical Association showing that 98% of the more than 10,000
CPIC and PGx discussed in recent GEN article
A recent article in Genetic Engineering & Biotechnology News (GEN) discusses the future of pharmacogenetics in the context of clinical practice. The article notes that personalized medicine will likely be enacted through the work of intermediary groups, such as the Clinical Pharmacogenetics Implementation Consortium (CPIC), who can help clinicians keep