CYP3A5 genotyping is a more accurate predictor of drug response than race alone
A new paper in Journal of Clinical Pharmacology from a group at Indiana University [PMID:37042314] implemented genotyping for CYP3A5 in a kidney transplant center.
The team used CPIC guidelines for tacrolimus dosing based on CYP3A5 genotype.
Implementation included provider education and clinical decision support in the electronic medical record.